In recent years, fentanyl and other toxic mescaline-based synthetics called NBOMEs (N-Benzylphenethylamine) have resulted in accidental overdoses. These synthetics share the same classification of drugs called phenethylamines, which may produce similar effects as mescaline, but carry a significantly higher risk of fatality. While these are rare events, they could be non-existent \u2014 if people had easy access to drug testing kits to verify the content of their substances. Ellis\u2019 trip report had a lasting impact, and before World War I a group of young philosophers and theologians were independently exploring the boundaries of mescaline while studying under existentialist philosopher Karl Jaspers at Heidelberg University.<\/p>\n

Subjective effects of the \u201cmost memorable\u201d mescaline experience<\/h2>\n

Of all the attempts to construct a religious practice around peyote, this was the one that survived. The Plains Indian peyote ceremony developed when the tribes were taken into forced captivity on the reservations. Before then, it was known only to those who visited the areas of Mexico and southern Texas where it grew \u2013 mostly Apache bands such as the Lipan and the Mescalero. But after the Texas-Mexico railroad opened in 1881, peyote from Texas began to reach the Comanche, Kiowa and Apache reservations in Oklahoma.<\/p>\n

Although there are some pharmacological differences between San Pedro, peyote and pure mescaline, I found they are all pretty similar in their effects. The physical weirdness isn\u2019t just side effects from the cactus, it\u2019s the same with the pure alkaloid too. When taking it on my own, or in an experimental session, I found myself absorbed in the sensations and the visuals.<\/p>\n

Psychedelics 101<\/h2>\n

In modern times, self-experimenters around the world are reporting a much wider range of benefits, including personal insights, mood enhancement, increased empathy and creativity, lifestyle changes, and even lucid dreams. Mescaline could also help reduce suicidal thoughts, according to researchers at the University of Alabama. Using data from the National Survey on Drug Use and Health, the researchers found that people who have used a psychedelic drug at least once in their life show lower rates of suicidal thinking. When taking mescaline, it\u2019s advised that you remove hazards, including sharp objects and things you might trip over.<\/p>\n

Research on Therapeutic Use<\/h2>\n

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• Edmund has an extensive background in addiction research and medical writing, working collaboratively with doctors, substance use disorder specialists, and clinical experts across all content on Recovered.<\/li>\n
• Overall, respondents reported that they had the most experience with SanPedro (45%).<\/li>\n
• French philosopher Jean-Paul Sartre entered a grotesque hell, whereas British writer Aldous Huxley tripped into a magnificent world of expanded consciousness, described in his influential 1954 book The Doors of Perception.<\/li>\n
• It would seem that this group of scholars and philosophers recognized that mescaline could be an intense experience for heightening self-awareness and phenomenological thought and analysis.<\/li>\n<\/ul>\n

  Microdosing is most often attributed to James Fadiman, author of The Psychedelic Explorer\u2019s Guide. However, Fadiman was initially informed about the process by Robert Forte, a psychedelic researcher and former Director of The Hoffman Foundation. Forte learned about microdosing from his teacher, the well-known Swiss chemist and the first person to synthesize LSD, Albert Hoffman. Forte shared the idea with psychologist James Fadiman, who wrote about it in The Psychedelic Explorer\u2019s Guide, which quickly gained interest by the public who liked the idea of mental health benefits without the psychedelic experience.<\/p>\n